Our methodology combines three pillars of biological age measurement — epigenetic clocks, blood biomarker analysis, and physical performance testing — each backed by rigorous science.
DNA methylation patterns change predictably with age. Epigenetic clocks measure these patterns to estimate biological age with remarkable accuracy.
The original multi-tissue epigenetic clock. Analyzes 353 CpG sites to estimate biological age across diverse tissue types.
Predicts time-to-death and lifespan. Incorporates smoking pack-years and plasma protein surrogates for superior mortality prediction.
Measures the pace of aging — how fast you're aging right now. Designed from longitudinal data tracking organ-system decline over time.
Not all interventions have the same level of evidence. We classify every protocol recommendation into three tiers so you know exactly what you're getting.
Multiple RCTs, meta-analyses, or large cohort studies support the intervention. These form the backbone of our protocols.
Supported by smaller RCTs, strong observational data, or compelling mechanistic evidence. Included with appropriate context.
Early-stage research with promising signals but limited human data. Flagged as experimental in our protocols.
The foundational research that informs our methodology.
Get a quick estimate of your biological age, then discover what real testing can reveal.
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